Eekhout Thomas

Eekhout Thomas - Postdoctoral fellow
Joined the group in 2014

Staff scientist

Thomas Eekhout graduated as a Master in Biochemistry and biotechnology at Ghent University in 2013 before starting his PhD on plant cell cycle regulation in the group of prof. Lieven De Veylder. After obtaining his PhD in 2018 he did a short postdoc in the same group, after which he joined the plant single cell platform of prof. Bert De Rybel in the summer of 2020. Since then, he has loaded and analyzed over two hundred samples from over 20 species for both internal and external groups on different single cell technology platforms.

23. Best practices for the execution, analysis, and data storage of plant single-cell/nucleus transcriptomics

Carolin Grones, Thomas Eekhout, Dongbo Shi, Manuel Neumann, Lea S Berg, Yuji Ke, Rachel Shahan, Kevin L Cox, Jr, Fabio Gomez-Cano, Hilde Nelissen, Jan U Lohmann, Stefania Giacomello, Olivier C Martin, Benjamin Cole, Jia-Wei Wang, Kerstin Kaufmann, Michael T Raissig, Gergo Palfalvi, Thomas Greb, Marc Libault, Bert De Rybel

(2024) - The Plant Cell

DOI
22. Scywalker: scalable end-to-end data analysis workflow for nanopore single-cell transcriptome sequencing

Peter De Rijk, Tijs Watzeels, Fahri Küçükali, Jasper Van Dongen, Júlia Faura, Patrick Willems, Lara De Deyn, Lena Duchateau, Carolin Grones, Thomas Eekhout, Tim De Pooter, Geert Joris, Stephane Rombauts, Bert De Rybel, Rosa Rademakers, Frank Van Breusegem, Mojca Strazisar, Kristel Sleegers, Wouter De Coster

(2024) -

DOI
21. Neoantigen-targeted dendritic cell vaccination in lung cancer patients induces long-lived T cells exhibiting the full differentiation spectrum

Joline Ingels, Laurenz De Cock, Dieter Stevens, Rupert L. Mayer, Fabien Théry, Guillem Sanchez Sanchez, David Vermijlen, Karin Weening, Saskia De Smet, Nele Lootens, Marieke Brusseel, Tasja Verstraete, Jolien Buyle, Eva Van Houtte, Pam Devreker, Kelly Heyns, Stijn De Munter, Sandra Van Lint, Glenn Goetgeluk, Sarah Bonte, Lore Billiet, Melissa Pille, Hanne Jansen, Eva Pascal, Lucas Deseins, Lies Vantomme, Maarten Verdonckt, Ria Roelandt, Thomas Eekhout, Niels Vandamme, Georges Leclercq, Tom Taghon, Tessa Kerre, Floris Vanommeslaeghe, Annemieke Dhondt, Liesbeth Ferdinande, Jo Van Dorpe, Liesbeth Desender, Frederic De Ryck, Frank Vermassen, Veerle Surmont, Francis Impens, Björn Menten, Karim Vermaelen, Bart Vandekerckhove

(2024) - Cell Reports Medicine

DOI
20. Dual and spatially resolved drought responses in the Arabidopsis leaf mesophyll revealed by single-cell transcriptomics

Rubén Tenorio Berrío, Eline Verhelst, Thomas Eekhout, Carolin Grones, Lieven De Veylder, Bert De Rybel, Marieke Dubois

(2024) -

DOI
19. PAT1-type GRAS-domain proteins control regeneration by activating DOF3.4 to drive cell proliferation in Arabidopsis roots

Anchal Bisht, Thomas Eekhout, Balkan Canher, Ran Lu, Ilse Vercauteren, Geert De Jaeger, Jefri Heyman, Lieven De Veylder

(2023) - The Plant Cell

DOI
18. Cell type–specific attenuation of brassinosteroid signaling precedes stomatal asymmetric cell division

Eun-Ji Kim, Cheng Zhang, Boyu Guo, Thomas Eekhout, Anaxi Houbaert, Jos R. Wendrich, Niels Vandamme, Manish Tiwari, Claire Simon--Vezo, Isabelle Vanhoutte, Yvan Saeys, Kun Wang, Yuxian Zhu, Bert De Rybel, Eugenia Russinova

(2023) - Proceedings of the National Academy of Sciences

DOI
17. Distinctive and complementary roles of E2F transcription factors during plant replication stress responses

Maherun Nisa, Thomas Eekhout, Clara Bergis, Jose-Antonio Pedroza-Garcia, Xiaoning He, Christelle Mazubert, Ilse Vercauteren, Toon Cools, Rim Brik-Chaouche, Jeannine Drouin-Wahbi, Layla Chmaiss, David Latrasse, Catherine Bergounioux, Klaas Vandepoele, Moussa Benhamed, Lieven De Veylder, Cécile Raynaud

(2023) - Molecular Plant

DOI
16. Plant lineage-specific PIKMIN1 drives APC/CCCS52A2 E3-ligase activity-dependent cell division

Alex Willems, Yuanke Liang, Jefri Heyman, Thomas Depuydt, Thomas Eekhout, Balkan Canher, Hilde Van den Daele, Ilse Vercauteren, Klaas Vandepoele, Lieven De Veylder

(2023) - Plant Physiology

DOI
15. A single-cell morpho-transcriptomic map of brassinosteroid action in the Arabidopsis root.

No contributors listed

(2021) - Molecular plant

DOI
14. Maize ATR safeguards genome stability during kernel development to prevent early endosperm endocycle onset and cell death

Jose Antonio Pedroza-Garcia, Thomas Eekhout, Ignacio Achon, Maher-Un Nisa, Griet Coussens, Ilse Vercauteren, Hilde Van den Daele, Laurens Pauwels, Mieke Van Lijsebettens, Cécile Raynaud, Lieven De Veylder

(2021) - The Plant Cell

DOI
13. Arabidopsis casein kinase 2 triggers stem cell exhaustion under Al toxicity and phosphate deficiency through activating the DNA damage response pathway

Pengliang Wei, Manon Demulder, Pascale David, Thomas Eekhout, Kaoru Okamoto Yoshiyama, Long Nguyen, Ilse Vercauteren, Dominique Eeckhout, Margot Galle, Geert De Jaeger, Paul Larsen, Dominique Audenaert, Thierry Desnos, Laurent Nussaume, Remy Loris, Lieven De Veylder

(2021) - The Plant Cell

DOI
12. A Mutation in DNA Polymerase α Rescues WEE1KO Sensitivity to HU

Thomas Eekhout, José Antonio Pedroza-Garcia, Pooneh Kalhorzadeh, Geert De Jaeger, Lieven De Veylder

(2021) - International Journal of Molecular Sciences

DOI
11. Non-cell autonomous and spatiotemporal signalling from a tissue organizer orchestrates root vascular development

BaoJun Yang, Max Minne, Federica Brunoni, Lenka Plačková, Ivan Petřík, Yanbiao Sun, Jonah Nolf, Wouter Smet, Kevin Verstaen, Jos R. Wendrich, Thomas Eekhout, Klára Hoyerová, Gert Van Isterdael, Jurgen Haustraete, Anthony Bishopp, Etienne Farcot, Ondřej Novák, Yvan Saeys, Bert De Rybel

(2021) - Nature Plants

DOI
10. G2/M-checkpoint activation in fasciata1 rescues an aberrant S-phase checkpoint but causes genome instability

Thomas Eekhout, Martina Dvorackova, José Antonio Pedroza Garcia, Martina Nespor Dadejova, Pooneh Kalhorzadeh, Hilde Van den Daele, Ilse Vercauteren, Jiri Fajkus, Lieven De Veylder

(2021) - Plant Physiology

DOI
9. The plant WEE1 kinase is involved in checkpoint control activation in nematode‐induced galls

Danila Cabral, Mohamed Youssef Banora, José Dijair Antonino, Natalia Rodiuc, Paulo Vieira, Roberta R. Coelho, Christian Chevalier, Thomas Eekhout, Gilbert Engler, Lieven De Veylder, Maria Fatima Grossi‐de‐Sa, Janice de Almeida Engler

(2020) - New Phytologist

DOI
8. Rocks in the auxin stream: Wound-induced auxin accumulation and ERF115 expression synergistically drive stem cell regeneration

Balkan Canher, Jefri Heyman, Maria Savina, Ajay Devendran, Thomas Eekhout, Ilse Vercauteren, Els Prinsen, Rotem Matosevich, Jian Xu, Victoria Mironova, Lieven De Veylder

(2020) - Proceedings of the National Academy of Sciences

DOI
7. The Cyclin CYCA3;4 Is a Postprophase Target of the APC/CCCS52A2 E3-Ligase Controlling Formative Cell Divisions in Arabidopsis

Alex Willems, Jefri Heyman, Thomas Eekhout, Ignacio Achon, Jose Antonio Pedroza-Garcia, Tingting Zhu, Lei Li, Ilse Vercauteren, Hilde Van den Daele, Brigitte van de Cotte, Ive De Smet, Lieven De Veylder

(2020) - The Plant Cell

DOI
6. Hitting pause on the cell cycle

Thomas Eekhout, Lieven De Veylder

(2019) - eLife

DOI
5. A Spatiotemporal DNA Endoploidy Map of the Arabidopsis Root Reveals Roles for the Endocycle in Root Development and Stress Adaptation

Rahul Bhosale, Veronique Boudolf, Fabiola Cuevas, Ran Lu, Thomas Eekhout, Zhubing Hu, Gert Van Isterdael, Georgina M. Lambert, Fan Xu, Moritz K. Nowack, Richard S. Smith, Ilse Vercauteren, Riet De Rycke, Veronique Storme, Tom Beeckman, John C. Larkin, Anna Kremer, Herman Höfte, David W. Galbraith, Robert P. Kumpf, Steven Maere, Lieven De Veylder

(2018) - The Plant Cell

DOI
4. Modification of DNA Checkpoints to Confer Aluminum Tolerance.

Eekhout T, Larsen P, De Veylder L

(2017) -

DOI
3. Tissue-Specific Control of the Endocycle by the Anaphase Promoting Complex/Cyclosome Inhibitors UVI4 and DEL1

Jefri Heyman, Stefanie Polyn, Thomas Eekhout, Lieven De Veylder

(2017) - Plant Physiology

DOI
2. Lack of RNase H2 activity rescues HU-sensitivity of WEE1 deficient plants.

Eekhout T, Kalhorzadeh P, De Veylder L

(2015) -

DOI
1. The Arabidopsis SIAMESE-RELATED cyclin-dependent kinase inhibitors SMR5 and SMR7 regulate the DNA damage checkpoint in response to reactive oxygen species.

Yi D, Alvim Kamei CL, Cools T, Vanderauwera S, Takahashi N, Okushima Y, Eekhout T, Yoshiyama KO, Larkin J, Van den Daele H, Conklin P, Britt A, Umeda M, De Veylder L

(2014) -

DOI